Nigeria's Paralympic champion Esther Oyema looked comfortable as she first equalled, then broke, her own world record twice on the way to victory in the women's -55kg.
The 31-year-old opened with 120kg, before lifting 123kg in round two to break the record she set in Kuala Lumpur in November 2013.
With a third-round flourish, Oyema hauled 125kg to further her world mark.
China's Shanshan Shi (115kg) finished in silver, whilst Russia's Anastasia Khonina (109kg) took bronze.
The junior title went to 19-year-old Italian Martina Barbierato (70kg).
The 2014 IPC Powerlifting World Championships have featured over 330 athletes from nearly 60 countries and were the first opportunity for athletes to begin qualification for the Rio 2016 Paralympic Games.
The competition also featured the climax to the "Raise the Bar campaign," which has seen powerlifters and team officials take part in education seminars as part of efforts to reduce doping in the sport.
For more information about the 2014 IPC Powerlifting World Championships, please visit the Dubai 2014 microsite: http://www.paralympic.org/dubai-2014
ARM Greta Vardanyan
CHN Shanshan Shi
CHN Hongchan Wang
GBR Natalie Blake
ITA Martina Barbierato
KAZ Gulbanu Abdykhalykova
NGR Esther Oyema
RUS Elena Machekhina
RUS Tamara Podpalnaya
RUS Anastasia Khonina
TUR Sibel Cam
VEN Wiunawis Nairobys Hernandez