Taking place in Central London, the event will bring together athletes and officials from previous Paralympic Games to share stories and celebrate their accomplishments while, at the same time, taking in action from London 2012.
Last year the IPC issued a survey to gauge the interest of Paralympians in a reunion and the response was overwhelming.
Sir Philip Craven, IPC President, said: "This is the first time that we have taken the step to reunite Paralympians from all over the world and it promises to be an evening to remember.
"Not only will be a chance for people to meet up with old teammates, but also old rivals who they may not have seen since competing against them in previous editions of the Paralympic Games."
To help Paralympians in planning their trips to London for September's Reunion, the IPC has appointed eVenture Zone, the IPC's official ticket and hospitality partner, to offer a number of four and five day packages to the event which also takes in sporting action from the London Games and the Closing Ceremony.
The first Paralympic Games took place in Rome in 1960 and since then the size of the event has grown exponentially. In London 4,200 athletes from 160 countries compete in 20 different sports.
To register for the Paralympian Reunion event, please contact Kim Liu, IPC Protocol & Events Manager at firstname.lastname@example.org by 2 March 2012.